249 research outputs found

    An Analysis of User-Generated Comments on the Development of Social Mobile Learning

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    In this study, the authors used a mixed-method approach to analyze user-generated comments on social mobile learning from three leading news sites that report the latest development in higher education. Koole’s mobile learning model was used to code comments made by the public on the three news sites. Results showed that social mobile learning has gained an increasing public engagement in the past four years. Responders’ discussion in the comments primarily focused on four themes of social mobile learning: technology adoption, effective design, faculty training, and student training. In the end, the authors discussed the implications for developers and educators and concluded with recommendations for future research in social mobile learning using user-generated comments

    Pandemic Pedagogy in Online Hands-on Learning for IT/IS Courses

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    Due to the coronavirus disease of 2019 (COVID-19) pandemic, many educational institutions have transitioned to online instruction. As a result, instructors need to investigate online small group learning opportunities to bond with their students who feel isolated from their peers due to social-distancing guidelines. In this paper, we discuss three key issues in online hands-on learning: 1) interactions, 2) equity and inclusive participation, and 3) students’ readiness for hands-on or higher-level cognitive learning. We reflect on our teaching experience during the COVID-19 pandemic and offer suggestions to help instructors plan and implement online small group hands-on learning

    Teaching Tip: Promoting Inclusive Online Learning for Students with Disabilities in Information Systems Courses

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    It is important to ensure educational equity for students with disabilities in online courses as more courses are taught online during the pandemic. This conceptual paper describes the key barriers for instructors to implement inclusive online classes, particularly technology courses, during the COVID-19 pandemic and suggests specific strategies to mitigate the negative impact on students with disabilities. We hope that this paper will motivate more Information Technology/Information Systems (IT/IS) instructors to implement more inclusive and accessible online courses to keep all students, including students with disabilities, motivated and engaged in online environments throughout the pandemic

    A Literature Review of Quantum Education in K-12 Level

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    Quantum computing is an emerging technology paradigm of computing and has the potential to solve computational problems intractable using today’s classical computers or digital technology. Quantum computing is expected to be disruptive for many industries. The power of quantum computing technologies is based on the fundamentals of quantum mechanics, such as quantum superposition, quantum entanglement, or the no-cloning theorem. To build a highly trained and skilled quantum workforce that meets future industry needs, there is a need to introduce quantum concepts early on in K-12 schools since the learning of quantum is a lengthy process. As fundamental quantum concepts derive from physics, students usually start to learn physics in secondary schools. Since the resources and curriculum design for quantum education in K-12 level is rare, we conducted a literature review with a focus on quantum computing education in K-12 level and filled the research gap

    A Coupled Model for Solution Flow and Bioleaching Reaction Based on the Evolution of Heap Pore Structure

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    Based on the basic seepage law, equations have been derived to descript the solution flow within the copper ore heap which is treated as anisotropy porous media. The relationship between heap permeability and pore ratio has been revealed. Given the consideration of cover pressure and particle dissolution, pore evolution model has been set up. The pore evolution mechanism, due to the process of dissolution, precipitation, blockage, collapse, and caking, has been investigated. The comprehensive model for pore evolution and solution flow under the effect of solute transport and leaching reaction has been established. A trapezoidal heap was calculated, and the estimated results show that permeability decreases with the decreasing of pore ratio. Therefore, the permeability of the heap with small particles is relatively low because of its low pore ratio. Furthermore, permeability and height are found to be the two main factors influencing the solution flow

    Changes in glomerular thromboxane A2 receptor expression and ligand binding following immune injury

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    Changes in glomerular thromboxane A2 receptor expression and ligand binding following immune injury.BackgroundThromboxane (Tx) A2 is a potent vasoconstrictor eicosanoid that attains high levels within nephritic glomeruli and mediates a drop in glomerular filtration rate (GFR). In the course of nephritis, however, GFR recovers despite high intraglomerular TxA2 levels. We hypothesized that this recovery indicates a reduced responsiveness of the glomerular vasculature to TxA2, and explored whether changes in TxA2 receptor protein expression and receptor-ligand binding are underlying mechanisms.MethodsGlomerulonephritis was induced in male Sprague-Dawley rats using an antibody raised in rabbits against rat particulate glomerular basement membrane (GBM). Changes in Tx receptor levels were assessed in protein lysates of glomeruli on days 3 and 7 after a single intravenous injection of the anti-GBM antibody. Ligand-binding studies were performed at the same time points using isolated glomeruli and the TxA2 receptor ligand [3H]-SQ-29,548. GFR was measured as the clearance of endogenous creatinine.ResultsThere was a marked increase in Tx receptor protein in the lysates of nephritic glomeruli on days 3 and 7. In contrast, binding sites (Bmax) of [3H]–SQ-29,548 decreased, indicating that the excess receptor became either inaccessible to its ligand (sequestered) or desensitized. Daily administration of the Tx synthase inhibitor Furegrelate starting prior to injection of anti-GBM antibody prevented the decrease in [3H]–SQ-29,548 binding. Furegrelate treatment starting in an established stage of nephritis had no effect. In these animals, GFR was lower than nephritic controls not treated with Furegrelate.ConclusionsThese observations indicate that in the course of glomerulonephritis, there is a marked increase in glomerular Tx receptor expression. The enhanced intraglomerular TxA2 synthesis causes either a sequestration or desensitization of its receptor. As a result, access of unbound TxA2 to efferent arterioles may become facilitated, and constriction of these arterioles may preserve GFR
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